Gene symbol | CCR5 | Synonyms | CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3p21.31 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | C-C motif chemokine receptor 5 |
GTO ID | GTC0318 |
Trial ID | NCT02797470 |
Disease | HIV Infection |
Altered gene | CCR5 |
Therapeutic/Target gene | Target gene |
Therapy | shRNA |
Treatment | CCR5 shRNA/TRIM5alpha/TAR decoy LV CD34+ cells |
Co-treatment | Carmustine|Cytarabine|Etoposide|Melphalan |
Phase | Phase1|Phase2 |
Recruitment status | Active, Not Recruiting |
Title | A Phase I Study of Stem Cell Gene Therapy for HIV Mediated by Lentivector Transduced, Pre-Selected CD34+ Cells |
Year | 2016 |
Country | United States |
Company sponsor | AIDS Malignancy Consortium |
Other ID(s) | AMC-097|NCI-2015-01745|9933|AMC 097|097|AMC-097|U01CA121947 |
Vector information | |||||
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Cohort 1 | |||||||||||
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