Basic Information

Gene symbol CTAG1B Synonyms CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 Type of gene protein-coding
Description cancer/testis antigen 1B

GTO ID GTC0314
Trial ID NCT02775292
Disease Solid Tumor
Altered gene NY-ESO-1
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment NY-ESO-1 TCR-T cells
Co-treatment Nivolumab
HLAHLA-A*02:01
PhasePhase1
Recruitment statusCompleted
TitleNY-ESO-1 TCR Engineered Adoptive Cell Transfer Therapy With Nivolumab PD-1 Blockade
Year2016
CountryUnited States
Company sponsorJonsson Comprehensive Cancer Center
Other ID(s)15-001433|NCI-2016-00201|R35CA197633|15-001433|K12HD000850
Vector information
Vectorretrovirus

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 1
Age Child, Adult, Older_Adult
Lymph depletion Yes
Adverse reactions no TCR related AEs
References PMID: 37156551

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