Basic Information

Gene symbol CTAG1B Synonyms CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 Type of gene protein-coding
Description cancer/testis antigen 1B

GTO ID GTC0313
Trial ID NCT02774291
Disease Metastatic Cancer
Altered gene NY-ESO-1
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment NY-ESO-1 TCR-T cells
Co-treatment Filgrastim
HLAHLA-A*02:01
PhasePhase1
Recruitment statusTerminated
TitlePilot Study of Adoptive Cell Transfer for the Treatment of Metastatic Cancer That Expresses NY-ESO-1 Using Lymphodepleting Conditioning Followed by Infusion of Anti-NY ESO-1 Murine TCR-Gene Engineered Lymphocytes
Year2016
CountryUnited States
Company sponsorAlbert Einstein College of Medicine
Other ID(s)2015-5254|NCI-2015-01781|2015-5254|P30CA013330

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 3
Age Adult, Older_Adult
Lymph depletion Yes
Adverse reactions 2/3(All-cause mortality)

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