Gene symbol | WT1 | Synonyms | AWT1, GUD, NPHS4, WAGR, WIT-2, WT-1, WT33 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11p13 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | WT1 transcription factor |
GTO ID | GTC0311 |
Trial ID | NCT02770820 |
Disease | Acute Myeloid Leukemia |
Altered gene | WT1 |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | WT1 TCR-T cells |
HLA | HLA-A*02:01 |
Phase | Phase1|Phase2 |
Recruitment status | Terminated |
Title | Phase I/II Study of Autologous (Central Memory/Naïve) CD8+ T Cells That Have Been Transduced to Express a WT1-Specific T Cell Receptor for Treatment of AML |
Year | 2016 |
Country | United States |
Company sponsor | Fred Hutchinson Cancer Center |
Other ID(s) | 9296|NCI-2016-00042|9296|P01CA018029|P30CA015704|RG9216011 |
Cohort 1 | |||||||||||||
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