Basic Information


GTO ID GTC0303
Trial ID NCT02719782
Disease Recurrent Hepatocellular Carcinoma
Altered gene X
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment HBV TCR-T cells
HLAHLA class I
PhasePhase1
Recruitment statusUnknown
TitleA Phase I Study T Cell Receptor-Redirected T Cells Infusions in Subjects With Recurrent HBV-Related Hepatocellular Carcinoma in Post Liver Transplantation
Year2016
CountryChina
Company sponsorLion TCR Pte. Ltd.
Other ID(s)LTCR-HCC-2-1
Vector information
Vectorelectroporation

Clinical Result

Cohort 1
Administration route infusion
Dosage 0.1~50E5 cells
Donor type autologous
Pts 6
Age Adult, Older_Adult
Lymph depletion No
Outcome 4/10(SD); 5/10(PD)
Adverse reactions 3/6(pyrexia)
References PMID: 37067675

Relationship Graph

Overview of Knowledge Graph