Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC0272 |
Trial ID | NCT02588456 |
Disease | B-Cell Acute Lymphoblastic Leukemia |
Altered gene | CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD22 CAR-T cells |
Generation | 2nd |
Phase | Phase1 |
Recruitment status | Terminated |
Title | Pilot Study of Autologous Anti-CD22 Chimeric Antigen Receptor Redirected T Cells In Patients With Chemotherapy Resistant Or Refractory Acute Lymphoblastic Leukemia |
Year | 2015 |
Country | United States |
Company sponsor | University of Pennsylvania |
Other ID(s) | UPCC 31415, 822967 |
Vector information | |||||||
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Cohort 1 | |||||||||||||||||||
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