Basic Information

Gene symbol IL12A Synonyms CLMF, IL-12A, NFSK, NKSF1, P35 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description interleukin 12A

Gene symbol IL12B Synonyms CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2 Type of gene protein-coding
Description interleukin 12B

GTO ID GTC0232
Trial ID NCT02345330
Disease Head and Neck Squamous Cell Carcinoma
Altered gene IL-12A|IL-12B
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment Tavokinogene Telseplasmid|tavo|pIL-12
PhasePhase2
Recruitment statusTerminated
TitleA Multicenter Phase II Trial of Intratumoral pIL-12 Electroporation in Treatment-Refractory Metastatic and Unresectable SCC of the Head and Neck
Year2015
CountryUnited States
Company sponsorOncoSec Medical Incorporated
Other ID(s)OMS-I130
Vector information
Vectorplasmid

Clinical Result

Cohort 1
Administration route intratumoral injection
Pts 4
Age Adult, Older_Adult
Adverse reactions 1/4(Neoplasms benign, malignant and unspecified, incl cysts and polyps)

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