Basic Information

Gene symbol TP53 Synonyms BCC7, BMFS5, LFS1, P53, TRP53 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description tumor protein p53

GTO ID GTC0229
Trial ID NCT02340117
Disease Pancreatic Cancer
Altered gene P53
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment SGT-53
PhasePhase2
Recruitment statusRecruiting
TitlePhase II Study of Combined Targeted p53 Gene Therapy (SGT-53) Plus Gemcitabine/Nab-Paclitaxel for Treatment of Metastatic Pancreatic Cancer
Year2014
CountryUnited States
Company sponsorSynerGene Therapeutics, Inc.
Other ID(s)SGT53-02-1
Vector information
Vectorplasmid

Clinical Result

Cohort 1
Administration route infusion
Dosage 3.6 mg
Pts 20
Age Adult, Older_Adult
Outcome 7/20(PR); 13/20(SD)
References DOI: 10.1200/JCO.2021.39.15_suppl.4139

Relationship Graph

Overview of Knowledge Graph