Basic Information

Gene symbol CTAG1B Synonyms CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 Type of gene protein-coding
Description cancer/testis antigen 1B

GTO ID GTC0179
Trial ID NCT01892293
Disease Multiple Myeloma
Altered gene NY-ESO-1
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment NY-ESO-1 TCR-T cells
HLAHLA-A2*01
PhasePhase1|Phase2
Recruitment statusTerminated
TitleA Phase I/IIa, Open Label, Multiple Site Clinical Trial Evaluating the Safety and Activity of Engineered Autologous T Cells Expressing an Affinity-enhanced TCR Specific for NY-ESO-1 and LAGE-1 in Patients With Relapsed or Progressive Disease in Multiple Myeloma
Year2013
CountryUnited States
Company sponsorAdaptimmune
Other ID(s)ADP-0011-002

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 2
Age Adult, Older_Adult
Lymph depletion Yes
Adverse reactions 2/2(All-cause mortality); 1/2(Injury, poisoning and procedural complications)

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