Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC0104
Trial ID NCT01245387
Disease Macular Degeneration | Age-Related Macular Degeneration
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
Recruitment statusCompleted
TitleLong-Term Non-Interventional Study (AB Study) To Investigate The Efficacy And Safety Of Macugen In Patients With Neovascular Age-Related Macular Degeneration Under Conditions Of Routine Clinical Practice
Year2006
CountryUnited States
Company sponsorPfizer
Other ID(s)A5751021

Clinical Result

Cohort 1
Administration route intravitreal injection
Dosage MACUGEN, 0.3 mg
Pts 1001
Age Adult, Older_Adult
Adverse reactions 16/816(Cardiac disorders; Eye disorders; Gastrointestinal disorders; Infections and infestations; Neoplasms benign, malignant and unspecified(incl cysts and polyps); Nervous system disorders)

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