Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC0069
Trial ID NCT00787319
Disease Age-Related Macular Degeneration
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
Recruitment statusCompleted
TitleLong-Term Non-Interventional Study (NIS) To Investigate The Safety And Effectiveness Of MACUGEN In Patients With Neovascular Age-Related Macular Degeneration Under Conditions Of Routine Clinical Practice
Year2010
CountryCzechia
Company sponsorPfizer
Other ID(s)A5751032

Clinical Result

Cohort 1
Administration route None
Pts 108
Age Adult, Older_Adult
Outcome Change From Baseline in Visual Acuity (VA) at Final Visit:Baseline Mean (Standard Deviation):0.61(0.27); Change at Final visit:0.15(0.37)
Adverse reactions 2/108(Eye disorders; Injury, poisoning and procedural complications)

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