Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC0064
Trial ID NCT00735943
Disease Macular Degeneration
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
Recruitment statusTerminated
TitleMacugen Observational Study
Year2008
CountryIndia
Company sponsorPfizer
Other ID(s)A5751031

Clinical Result

Cohort 1
Administration route intravitreal injection
Pts 22
Age Adult, Older_Adult
Outcome Percentage of Participants Showing Stabilization, Improvement or Deterioration of Visual Acuity (VA):Improvement Measure Type: Number:18.2; Stabilization:54.5; Deterioration:18.2|Average Number of Injections to Achieve Stabilization of VA:Mean (Standard Deviation):2.25(1.14)|Median Number of Injections to Achieve Stabilization of VA:Median (Full Range):2.00(1.00 to 4.00)
Adverse reactions No serious clinical adverse events

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