Gene symbol | MLANA | Synonyms | MART-1, MART1 | Type of gene | protein-coding |
Chromosome | 9 | Map location | 9p24.1 | dbXrefs | |
Description | melan-A |
GTO ID | GTC0053 |
Trial ID | NCT00612222 |
Disease | Metastatic Melanoma | Skin Cancer |
Altered gene | MART-1 |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | MAGE-A1 F5 TCR-T cells |
Co-treatment | ALVAC gp100 Vaccine |
HLA | HLA-A*02:01 |
Phase | Phase2 |
Recruitment status | Terminated |
Title | Phase II Study of Metastatic Melanoma Using Lymphodepleting Conditioning Followed by Infusion of Anti-MART-1 F5 TCR-Gene Engineered Lymphocytes and ALVAC Virus Immunization |
Year | 2008 |
Country | United States |
Company sponsor | National Cancer Institute (NCI) |
Other ID(s) | 080056|08-C-0056 |
Vector information | |||
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Cohort 1 | |||||||||||||||
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