Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC0044
Trial ID NCT00549055
Disease Age-Related Macular Degeneration
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
Recruitment statusCompleted
TitleA Study On The Efficacy Of Macugen Injections In Patients With Neovascular Age-Related Macular Degeneration (AMD) In Real Life (Macureli Study)
Year2007
CountryBelgium
Company sponsorPfizer
Other ID(s)A5751026

Clinical Result

Cohort 1
Administration route intravitreal injection
Dosage Macugen, 0.3mg, every 6 weeks (9 injections/year)
Pts 38
Age Child, Adult, Older_Adult
Outcome Change From Baseline to Final Visit in Visual Acuity (VA) Score:Mean (Standard Deviation):-0.044(0.122)
Adverse reactions No serious clinical adverse events

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