Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC0023
Trial ID NCT00239928
Disease Macular Degeneration
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
PhasePhase2
Recruitment statusCompleted
TitleLong-Term Study For Pegaptanib Sodium In Patients With Subfoveal Choroidal Neovascularization Secondary To Age-Related Macular Degeneration (Extension Study From A5751010)
Year2005
CountryJapan
Company sponsorPfizer
Other ID(s)A5751015

Clinical Result

Cohort 1
Administration route None
Dosage pegaptanib sodium, 1 drop per dosed eye per protocol
Pts 61
Age Adult, Older_Adult
Adverse reactions 16/61(Cardiac disorders; Eye disorders; Gastrointestinal disorders; General disorders; Infections and infestations; Injury, poisoning and procedural complications; Neoplasms benign, malignant and unspecified(incl cysts and polyps); Nervous system disorders; Vascular disorders)

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