Gene symbol | BCL2 | Synonyms | Bcl-2, PPP1R50 | Type of gene | protein-coding |
Chromosome | 18 | Map location | 18q21.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | BCL2 apoptosis regulator |
GTO ID | GTC0015 |
Trial ID | NCT00085228 |
Disease | Prostate Cancer |
Altered gene | Bcl-2 |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | Genasense|G3139|oblimersen sodium |
Co-treatment | docetaxel |
Phase | Phase2 |
Recruitment status | Completed |
Title | Randomized Phase II Trial of Docetaxel (Taxotere) and Oblimersen (Antisense Oligonucleotide Directed to BCL-2) Versus Taxotere Alone in Patients With Hormone-Refractory Prostate Cancer |
Year | 2004 |
Country | Austria|Belgium|Denmark|France|Israel|Italy|Netherlands|Poland|Portugal|Spain|United Kingdom |
Company sponsor | European Organisation for Research and Treatment of Cancer - EORTC |
Other ID(s) | EORTC-30021|EORTC-30021|AVENTIS-AVE3139E/2501 |
Vector information | |||
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Cohort 1 | |||||||||||||
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