Gene symbol | BCL2 | Synonyms | Bcl-2, PPP1R50 | Type of gene | protein-coding |
Chromosome | 18 | Map location | 18q21.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | BCL2 apoptosis regulator |
GTO ID | GTC0013 |
Trial ID | NCT00063934 |
Disease | Breast Cancer |
Altered gene | Bcl-2 |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | Genasense|G3139|oblimersen sodium |
Co-treatment | doxorubicin hydrochloride|docetaxel|filgrastim|pegfilgrastim|therapeutic conventional surgery |
Phase | Phase1|Phase2 |
Recruitment status | Terminated |
Title | A Phase 1/2 Study of Bcl-2 Antisense Oligonucleotide G3139 in Combination With Doxorubicin and Docetaxel in Metastatic and Locally Advanced Breast Cancer |
Year | 2003 |
Country | United States |
Company sponsor | National Cancer Institute (NCI) |
Other ID(s) | NCI-2012-02885|NCI-2012-02885|6023|DM02-700|6023|P30CA016672|N01CM17003 |
Vector information | |||
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Cohort 1 | |||||||||||
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