Basic Information

Gene symbol B2M Synonyms AMYLD6, IMD43, MHC1D4 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description beta-2-microglobulin

Gene symbol HLA-B Synonyms AS, B-4901, HLAB Type of gene protein-coding
Description major histocompatibility complex, class I, B

GTO ID GTC0009
Trial ID NCT00044356
Disease Melanoma | Skin Cancer
Altered gene HLA-B|B2m
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment Allovectin-7
PhasePhase2
Recruitment statusCompleted
TitleA Phase II Study of High-Dose Allovectin-7 in Patients With Advanced Metastatic Melanoma
Year2002
CountryUnited States
Company sponsorVical
Other ID(s)VCL-1005-208
Vector information
Vectorcationic liposome

Clinical Result

Cohort 1
Administration route intratumoral injection
Pts 133
Age Adult, Older_Adult
Outcome 15/127(OR, 13.8 months)
References PMID: 20354459

Relationship Graph

Overview of Knowledge Graph