Basic Information
| Drug ID | DDPD14761 |
|
| Drug Name | Remdesivir | |
| Molecular Weight | 602.585 | |
| Molecular Formula | C27H35N6O8P | |
| CAS Number | 1809249-37-3 | |
| SMILES | CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@H]1O[C@](C#N)([C@H](O)[C@@H]1O)C1=CC=C2N1N=CN=C2N)OC1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB14761 | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| AUC | 1585.0 | ng.h/ml | 1585 | ng.h/ml | intravenous injection, IV; | DRUGBANK | AUC | 462.0 | ng.h/ml | 462 | ng.h/ml | intravenous injection, IV; Metabolite; | DRUGBANK | AUC | 2229.0 | ng.h/ml | 2229 | ng.h/ml | intravenous injection, IV; Metabolite; | DRUGBANK |
| C Max | 2229.0 | ng/ml | 2229 | ng/ml | intravenous injection, IV; | DRUGBANK | C Max | 145.0 | ng/ml | 145 | ng/ml | intravenous injection, IV; Metabolite; | DRUGBANK | C Max | 246.0 | ng/ml | 246 | ng/ml | intravenous injection, IV; Metabolite; | DRUGBANK |
| T Max | 0.68 | h | 0.67-0.68 | h | intravenous injection, IV; | DRUGBANK | T Max | 1.8 | h | 1.51-2.00 | h | intravenous injection, IV; Metabolite; | DRUGBANK | T Max | 0.75 | h | 0.75 | h | intravenous injection, IV; Metabolite; | DRUGBANK |
| Half-life | 0.39 | h | 0.39 | h | elimination half-life; intravenous injection, IV; non-human primate; | DRUGBANK | Half-life | 14.0 | h | 14 | h | Metabolite; non-human primate; | DRUGBANK | Half-life | 20.0 | h | ~20 | h | Metabolite; human, homo sapiens; | DRUGBANK |
| Eliminate Route | 74.0 | % | 74 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 18.0 | % | 18 | % | Faeces excretion; | DRUGBANK |
| Protein Binding | 90.8 | % | 88-93.6 | % | plasma proteins; human, homo sapiens; | DRUGBANK | Protein Binding | 2.0 | % | 2 | % | plasma proteins; human, homo sapiens; Metabolite; | DRUGBANK | Protein Binding | 1.0 | % | 1 | % | plasma proteins; human, homo sapiens; Metabolite; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1