DETAILS

Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID	DDPD14598
Drug Name	Edetate calcium disodium anhydrous
Molecular Weight	374.268
Molecular Formula	C10H12CaN2Na2O8
CAS Number	62-33-9
SMILES	[Na+].[Na+].[Ca++].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O
External Links
	DRUGBANK	DB14598
	PubChem Compound	6109
	PDR	2852

Experimental Physicochemical Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Reference
Melting Point	300.0	℃	>300	℃	Budavari, 1989

Pharmacokinetic/ Toxicokinetic Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Reference
Absorption	5.0	%	5.0	%	PO, oral;	DRUGBANK
Metabolic	0	%	~0	%		DRUGBANK
Clearance	1.9	L/h/m2	54.6	ml/min/1.73m2	Average clearance; Neonates;	DRUGBANK
Clearance	4.0	L/h/m2	113.9±24.4	ml/min/1.73m2	Average clearance; Children; Adolescents;	DRUGBANK
Volume of Distribution	0.19	L/kg	0.19±0.10	L/kg		DRUGBANK
Half-life	0.67	h	20-60	min		DRUGBANK
Eliminate Route	95.0	%	95	%	Urinary excretion;	DRUGBANK
Eliminate Route	88.3	%	88.32	%	Faeces excretion; PO, oral; Rattus, Rat;	DRUGBANK
Eliminate Route	10.3	%	10.3	%	Urinary excretion; PO, oral; Rattus, Rat;	DRUGBANK

Maximum Dosage

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Brand Name	Component	Reference
Max dose for infants	1500.0	mg/m2/day	1500	mg/m2/day	intravenous injection, IV;IM,intramuscular injection;	Calcium Disodium Versenate	edetate calcium disodium	PDR
Max dose for children	1500.0	mg/m2/day	1500	mg/m2/day	intravenous injection, IV;IM,intramuscular injection;	Calcium Disodium Versenate	edetate calcium disodium	PDR
Max dose for adolescents	1500.0	mg/m2/day	1500	mg/m2/day	intravenous injection, IV;IM,intramuscular injection;	Calcium Disodium Versenate	edetate calcium disodium	PDR
Max dose for adults	1500.0	mg/m2/day	1500	mg/m2/day	intravenous injection, IV;IM,intramuscular injection;	Calcium Disodium Versenate	edetate calcium disodium	PDR
Max dose for elderly	1500.0	mg/m2/day	1500	mg/m2/day	intravenous injection, IV;IM,intramuscular injection;	Calcium Disodium Versenate	edetate calcium disodium	PDR

Drug Property Radar Chart

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1