Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD14509 ...
Drug Name Lithium carbonate
Molecular Weight 73.89
Molecular Formula CLi2O3
CAS Number 554-13-2
SMILES [Li+].[Li+].[O-]C([O-])=O
External Links
DRUGBANK DB14509
PDR 2719

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Boiling Point 1336.0 ℃ 1336 ℃ http://www.ilo.org/dyn/icsc/showcard.display?p_card_id=0710
Melting Point 180.5 ℃ 180.5 ℃ http://www.ilo.org/dyn/icsc/showcard.display?p_card_id=0710
Water Solubility 100.0 mM 100 mM http://www.chemspider.com/Chemical-Structure.10654.html

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Absorption 1.0 % ~100 % PO, oral; DRUGBANK
Metabolic 0 % 0 % DRUGBANK
Clearance 1.5 L/h 10-40 ml/min normal,healthy; DRUGBANK
Clearance 0.90 L/h 15.0 ml/min Geriatric; RD, renal impairment, Renal disease，including uremia; DRUGBANK
Volume of Distribution 0.85 L/kg 0.7-1 L/kg Apparent volume of distribution; DRUGBANK
Half-life 27.0 h 18-36 h DRUGBANK
Half-life 13.5 h 7-20 h different study; DRUGBANK
Toxicity LD50 525.0 mg/kg 525.0 mg/kg PO, oral; Rattus, Rat; DRUGBANK
Toxicity LC50 2.2 mg/L >2.17 mg/L inhalation, IH; Rattus, Rat; DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for children 1.5 mEq/L 1.5 mEq/L PO, oral Lithium Carbonate Capsules and Tablets, Lithium Oral Solution (lithium); (lithium carbonate) PDR
Max dose for children 1500.0 mg/day 1500 mg/day PO, oral Lithium Carbonate Capsules and Tablets, Lithium Oral Solution (lithium); (lithium carbonate) PDR
Max dose for children 1200.0 mg/day 1200 mg/day PO, oral Lithium Carbonate Capsules and Tablets, Lithium Oral Solution (lithium); (lithium carbonate) PDR
Max dose for children 1800.0 mg/day 1800 mg/day PO, oral Lithium Carbonate Capsules and Tablets, Lithium Oral Solution (lithium); (lithium carbonate) PDR
Max dose for children 1.5 mEq/L 1.5 mEq/L PO, oral Lithium Carbonate Capsules and Tablets, Lithium Oral Solution (lithium); (lithium carbonate) PDR
Max dose for children 20.0 mg/kg/day 20 mg/kg/day PO, oral Lithium Carbonate Capsules and Tablets, Lithium Oral Solution (lithium); (lithium carbonate) PDR
Max dose for adolescents 1.5 mEq/L 1.5 mEq/L PO, oral Lithium Carbonate Capsules and Tablets, Lithium Oral Solution (lithium); (lithium carbonate) PDR
Max dose for adolescents 1500.0 mg/day 1500 mg/day PO, oral Lithium Carbonate Capsules and Tablets, Lithium Oral Solution (lithium); (lithium carbonate) PDR
Max dose for adults 1.5 mEq/L 1.5 mEq/L PO, oral Lithium Carbonate Capsules and Tablets, Lithium Oral Solution (lithium); (lithium carbonate) PDR
Max dose for adults 1500.0 mg/day 1500 mg/day PO, oral Lithium Carbonate Capsules and Tablets, Lithium Oral Solution (lithium); (lithium carbonate) PDR
Max dose for geriatric 1.5 mEq/L 1.5 mEq/L PO, oral Lithium Carbonate Capsules and Tablets, Lithium Oral Solution (lithium); (lithium carbonate) PDR
Max dose for geriatric 1500.0 mg/day 1500 mg/day PO, oral Lithium Carbonate Capsules and Tablets, Lithium Oral Solution (lithium); (lithium carbonate) PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1