| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| Clearance |
0.32 |
L/h/kg |
0.32±0.11 |
L/h/kg |
Rattus, Rat; intravenous injection, IV; |
DRUGBANK |
| Volume of Distribution |
268.0 |
L |
268.0 |
L |
Apparent volume of distribution; IM,intramuscular injection; |
DRUGBANK |
| Half-life |
769.2 |
h |
29.2-34.9 |
day |
elimination half-life; |
DRUGBANK |
| Toxicity LD50 |
60.0 |
mg |
>60 |
mg |
IM,intramuscular injection; Rattus, Rat; |
DRUGBANK |
Toxicity LD50 |
750.0 |
mg/kg |
750.0 |
mg/kg |
PO, oral; Female, women; Rattus, Rat; |
DRUGBANK |
Toxicity LD50 |
965.0 |
mg/kg |
965.0 |
mg/kg |
PO, oral; Male, men; Rattus, Rat; |
DRUGBANK |
Toxicity LD50 |
2000.0 |
mg/kg |
>2000 |
mg/kg |
PO, oral; monkey; |
DRUGBANK |
| Eliminate Route |
1.0 |
% |
<1 |
% |
Urinary excretion; PO, oral; Unchanged drug; |
DRUGBANK |
Eliminate Route |
18.0 |
% |
~18 |
% |
Faeces excretion; PO, oral; Unchanged drug; |
DRUGBANK |
| Protein Binding |
99.0 |
% |
>99 |
% |
|
DRUGBANK |
