Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 193.5 | ℃ | 192-195 | ℃ | MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 0.95 | % | 0.95±0.04 | % | PO, oral; | DRUGBANK |
| Clearance | 1.1 | L/h | 18.7±3.9 | ml/min | Total clearance; | DRUGBANK | Clearance | 13.9 | L/h | 232±64 | ml/min | Plasma clearance; | DRUGBANK |
| Volume of Distribution | 10.9 | L | 10.9±2.0 | L | Apparent volume of distribution; | DRUGBANK | Volume of Distribution | 136.0 | L | 136±36 | L | Total volume of distribution; | DRUGBANK |
| Half-life | 11.0 | h | 10-12 | h | elimination half-life; | DRUGBANK |
| Toxicity LD50 | 6800.0 | mg/kg | 6800.0 | mg/kg | PO, oral; mouse; | DRUGBANK |
| Eliminate Route | 97.0 | % | 97 | % | Urinary excretion; PO, oral; | DRUGBANK |
| Protein Binding | 85.0 | % | ~85 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1