| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| Bioavailability |
73.5 |
% |
42-105 |
% |
PO, oral; Rattus, Rat; |
DRUGBANK |
Bioavailability |
58.5 |
% |
34-83 |
% |
PO, oral; dog; |
DRUGBANK |
Bioavailability |
49.5 |
% |
37-62 |
% |
PO, oral; monkey; |
DRUGBANK |
| T Max |
0.50 |
h |
0.5 |
h |
intravenous infusion, IV in drop; patients; |
DRUGBANK |
T Max |
0.50 |
h |
0.5 |
h |
intravenous infusion, IV in drop; normal,healthy; |
DRUGBANK |
| Clearance |
0.30 |
L/h |
0.3±9.2 |
L/h |
Average clearance; Oral single dose; |
DRUGBANK |
| Volume of Distribution |
124.0 |
L |
124±76 |
L |
Average volume of distribution; normal,healthy; |
DRUGBANK |
Volume of Distribution |
296.0 |
L |
296±535 |
L |
Average volume of distribution; patients; |
DRUGBANK |
| Half-life |
80.0 |
h |
80±29 |
h |
elimination half-life; tumor; patients; |
DRUGBANK |
| Eliminate Route |
4.0 |
% |
3.95 |
% |
Urinary excretion; PO, oral; |
DRUGBANK |
Eliminate Route |
70.7 |
% |
70.7 |
% |
Faeces excretion; PO, oral; |
DRUGBANK |
| Protein Binding |
99.0 |
% |
>99 |
% |
plasma proteins; |
DRUGBANK |
