Basic Information
| Drug ID | DDPD13995 |
|
| Drug Name | Ferric pyrophosphate citrate | |
| Molecular Weight | 1321.571 | |
| Molecular Formula | C18H24Fe4O42P6 | |
| CAS Number | 1802359-96-1 | |
| SMILES | [Fe+3].[Fe+3].[Fe+3].[Fe+3].OP(O)(=O)OP(O)(O)=O.OP(O)(=O)OP(O)(O)=O.OP([O-])(=O)OP([O-])([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | |
| External Links | ||
| DRUGBANK | DB13995 | |
| PDR | 3682 | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Boiling Point | 309.6 | ℃ | 309.6 | ℃ | 'MSDS-online' |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Factor | Reference |
|---|---|---|---|---|---|---|---|
| AUC | 12575.0 | ng.h/ml | 675-1840 | mcg.h/dl | increasing doses ↑ ; | DRUGBANK | |
| Bioavailability | 88.5 | % | 83-94 | % | DRUGBANK | ||
| C Max | 1870.0 | ng/ml | 113-261 | mcg/dl | increasing doses ↑ ; | DRUGBANK | |
| T Max | 4.5 | h | 4.5 | h | DRUGBANK | ||
| Clearance | 0.48 | L/h | 0.406-0.556 | L/h | Average clearance; | DRUGBANK | |
| Volume of Distribution | 0.81 | L | 0.765-0.859 | L | Apparent volume of distribution; intravenous injection, IV; | DRUGBANK | |
| Half-life | 1.5 | h | 1.48 | h | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 1.5 | mg/kg/dose | 1.5 | mg/kg/dose | intravenous injection, IV | Triferic | ferric pyrophosphate citrate | PDR |
| Max dose for children | 125.0 | mg/dose | 125 | mg/dose | intravenous injection, IV | Triferic | ferric pyrophosphate citrate | PDR |
| Max dose for adolescents | 1.5 | mg/kg/dose | 1.5 | mg/kg/dose | intravenous injection, IV | Triferic | ferric pyrophosphate citrate | PDR |
| Max dose for adolescents | 125.0 | mg/dose | 125 | mg/dose | intravenous injection, IV | Triferic | ferric pyrophosphate citrate | PDR |
| Max dose for adults | 125.0 | mg/dose | 125 | mg/dose | intravenous injection, IV | Triferic | ferric pyrophosphate citrate | PDR |
| Max dose for adults | 6.75 | mcg/kg | 6.75 | mg/dose | intravenous injection, IV | Triferic | ferric pyrophosphate citrate | PDR |
| Max dose for geriatric | 125.0 | mg/dose | 125 | mg/dose | intravenous injection, IV | Triferic | ferric pyrophosphate citrate | PDR |
| Max dose for geriatric | 6.75 | mg/dose | 6.75 | mg/dose | intravenous injection, IV | Triferic | ferric pyrophosphate citrate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1