Basic Information
| Drug ID | DDPD13925 |
|
| Drug Name | Dotatate gallium Ga-68 | |
| Molecular Weight | 1500.54 | |
| Molecular Formula | C65H87GaN14O19S2 | |
| CAS Number | 1027785-90-5 | |
| SMILES | [68Ga+3].C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)CN2CCN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC([O-])=O)CC2)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@H](CC2=CNC3=C2C=CC=C3)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(O)=O | |
| External Links | ||
| DRUGBANK | DB13925 | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -3.69 | - | -3.69 | - | Schottelius M., et al. EJNMMI Res. 2015; 5: 22. |
| Radioactivity | 5.0 | - | 5.0 | - | 'FDA label' |
| pKa | 2.6 | - | 2.6 | - | Long, N., Wong W. The Chemistry of Molecular Imaging. (2015) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Volume of Distribution | 0.000450 | L/m3 | 0.25-0.65 | ml/cm3 | DRUGBANK | |
| Half-life | 1.1 | h | 68 | min | DRUGBANK | |
| Eliminate Route | 12.0 | % | ~12 | % | Urinary excretion; intravenous injection, IV; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1