Basic Information
| Drug ID | DDPD13879 |
|
| Drug Name | Glecaprevir | |
| Molecular Weight | 838.87 | |
| Molecular Formula | C38H46F4N6O9S | |
| CAS Number | 1365970-03-1 | |
| SMILES | [H][C@@]12CN(C(=O)[C@@]([H])(NC(=O)O[C@]3([H])CCC[C@@]3([H])OC\C=C\C(F)(F)C3=NC4=C(C=CC=C4)N=C3O1)C(C)(C)C)[C@@]([H])(C2)C(=O)N[C@@]1(C[C@H]1C(F)F)C(=O)NS(=O)(=O)C1(C)CC1 | |
| External Links | ||
| DRUGBANK | DB13879 | |
| PubChem Compound | 66828839 | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Water Solubility | 200.0 | mg/L | <0.1-0.3 | mg/ml | FDA Label |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| C Max | 597.0 | ng/ml | 597 | ng/ml | Hepatitis, Hep; | DRUGBANK |
| T Max | 5.0 | h | 5 | h | normal,healthy; | DRUGBANK |
| Half-life | 6.0 | h | ~6 | h | elimination half-life; | DRUGBANK |
| Eliminate Route | 92.1 | % | 92.1 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 0.70 | % | 0.7 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 97.5 | % | >97.5 | % | plasma proteins; human, homo sapiens; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1