Basic Information
| Drug ID | DDPD13878 |
|
| Drug Name | Pibrentasvir | |
| Molecular Weight | 1113.201 | |
| Molecular Formula | C57H65F5N10O8 | |
| CAS Number | 1353900-92-1 | |
| SMILES | CO[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1C1=NC2=C(N1)C=C(F)C(=C2)[C@H]1CC[C@@H](N1C1=CC(F)=C(N2CCC(CC2)C2=CC=C(F)C=C2)C(F)=C1)C1=CC2=C(NC(=N2)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC)C=C1F | |
| External Links | ||
| DRUGBANK | DB13878 | |
| PubChem Compound | 58031952 | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Water Solubility | 100.0 | mg/L | <0.1 | mg/ml | FDA Label |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| C Max | 110.0 | ng/ml | 110 | ng/ml | Hepatitis, Hep; | DRUGBANK |
| T Max | 5.0 | h | 5 | h | normal,healthy; | DRUGBANK |
| Metabolic | 0 | % | 0 | % | DRUGBANK | |
| Half-life | 13.0 | h | ~13 | h | elimination half-life; | DRUGBANK |
| Eliminate Route | 96.6 | % | 96.6 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 0 | % | 0 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 99.9 | % | >99.9 | % | plasma proteins; human, homo sapiens; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1