Basic Information
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 57.0 | % | 57 | % | Oral single dose; | DRUGBANK |
| C Max | 1300.0 | ng/ml | 1.3 | mcg/ml | Oral single dose; | DRUGBANK |
| Tss | 696.0 | h | 29 | day | Oral single dose; | DRUGBANK |
| Metabolic | 11.0 | % | 11 | % | DRUGBANK | |
| Clearance | 0.74 | L/h | 0.74 | L/h | Average clearance; | DRUGBANK |
| Volume of Distribution | 55.8 | L | 55.8 | L | Average volume of distribution; | DRUGBANK |
| Half-life | 137.0 | h | 137 | h | terminal half-life; | DRUGBANK |
| Eliminate Route | 89.0 | % | 89 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 11.0 | % | 11 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 34.0 | % | 34 | % | Faeces excretion; Unchanged drug; | DRUGBANK | Eliminate Route | 0.40 | % | 0.4 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
| Protein Binding | 98.5 | % | 98.5 | % | plasma proteins; human, homo sapiens; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 100.0 | mg/day | 100 | mg/day | PO, oral | Idhifa | enasidenib | PDR |
| Max dose for geriatric | 100.0 | mg/day | 100 | mg/day | PO, oral | Idhifa | enasidenib | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1