Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD13873 ...
Drug Name Fenofibric acid
Molecular Weight 318.75
Molecular Formula C17H15ClO4
CAS Number 42017-89-0
SMILES CC(C)(OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1)C(O)=O
External Links
DRUGBANK DB13873
PubChem Compound 64929
PDR 1203

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 82.8 % ~82.75 % Liquid; normal,healthy; food; DRUGBANK
T Max 2.5 h 2.5 h Liquid; normal,healthy; food; DRUGBANK
Clearance 1.2 L/h 1.2 L/h Oral single dose; Elderly; DRUGBANK
Clearance 1.1 L/h 1.1 L/h Oral single dose; young; adults; DRUGBANK
Volume of Distribution 70.9 L 70.9±27.5 L DRUGBANK
Half-life 20.0 h ~20 h DRUGBANK
Toxicity LD50 1242.0 mg/kg 1242.0 mg/kg PO, oral; Rattus, Rat; DRUGBANK
Toxicity LD50 100.0 mg/kg 100.0 mg/kg PO, oral; mouse; DRUGBANK
Toxicity LD50 500.0 mg/kg 500.0 mg/kg Intraperitoneal, IP; mouse; DRUGBANK
Protein Binding 99.0 % ~99 % hyperlipoidemia; normal,healthy; human, homo sapiens; DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for adults 135.0 mg/day 135 mg/day Capsule, PO, Oral Fibricor fenofibric acid PDR
Max dose for adults 105.0 mg/day 105 mg/day Tablet,PO，oral Fibricor fenofibric acid PDR
Max dose for elderly 135.0 mg/day 135 mg/day Capsule, PO, Oral Fibricor fenofibric acid PDR
Max dose for elderly 105.0 mg/day 105 mg/day Tablet,PO，oral Fibricor fenofibric acid PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1