Basic Information
| Drug ID | DDPD13751 |
|
| Drug Name | Glycyrrhizic acid | |
| Molecular Weight | 822.942 | |
| Molecular Formula | C42H62O16 | |
| CAS Number | 1405-86-3 | |
| SMILES | [H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](O[C@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)C(O)=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O | |
| External Links | ||
| DRUGBANK | DB13751 | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.8 | - | 2.8 | - | 'MSDS' |
| Boiling Point | 200.0 | ℃ | 200 | ℃ | 'MSDS' |
| Melting Point | 220.0 | ℃ | (Decomposes at 200 ) | ℃ | 'MSDS' |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.0205 | L/h/kg | 16-25 | ml/h/kg | DRUGBANK | |
| Volume of Distribution | 0.0505 | L/kg | 37-64 | ml/kg | Total volume of distribution; | DRUGBANK | Volume of Distribution | 0.0785 | L/kg | 59-98 | ml/kg | Apparent volume of distribution; at steady state; | DRUGBANK |
| Half-life | 3.5 | h | 3.5 | h | elimination half-life; dose; | DRUGBANK |
| Toxicity LD50 | 6504.0 | mg/kg | 308-12700 | mg/kg | DRUGBANK | |
| Eliminate Route | 1.8 | % | ~1.1-2.5 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 1.8 | % | ~1.1-2.5 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1