Basic Information
| Drug ID | DDPD13615 |
|
| Drug Name | Mifamurtide | |
| Molecular Weight | 1277.515 | |
| Molecular Formula | C59H110N6NaO20P | |
| CAS Number | 838853-48-8 | |
| SMILES | O.[Na+].CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCCNC(=O)[C@H](C)NC(=O)CC[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@@H]([C@H](O)[C@H](O)CO)[C@@H](NC(C)=O)C=O)C(N)=O)OC(=O)CCCCCCCCCCCCCCC | |
| External Links | ||
| DRUGBANK | DB13615 | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| AUC | 21717.8 | ng.h | 17.0±4.86 | nM.h | intravenous injection, IV; normal,healthy; adults; | DRUGBANK |
| C Max | 20.1 | ng/ml | 15.7±3.72 | nMol/L | intravenous injection, IV; normal,healthy; adults; | DRUGBANK |
| Clearance | 34.0 | L/h | 565-569 | ml/min | Average clearance; intravenous infusion, IV in drop; normal,healthy; | DRUGBANK | Clearance | 2.9 | L/h/kg | 48.7 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 126.9 | L | 225-28.7 | L | Average volume of distribution; at steady state; intravenous infusion, IV in drop; normal,healthy; | DRUGBANK | Volume of Distribution | 5.8 | L/kg | 5.8 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 2.1 | h | 2.05±0.40 | h | normal,healthy; adults; intravenous injection, IV; | DRUGBANK | Half-life | 2.0 | h | 2.04±0.456 | h | psteosarcoma; pediatric patients; adults; patients; | DRUGBANK | Half-life | 2.1 | h | 2.05 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1