Basic Information
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 2.5 | h | 1-4 | h | PO, oral; | DRUGBANK | T Max | 2.5 | h | 1-4 | h | Rectal Administration; | DRUGBANK |
| Clearance | 2.1 | L/h | 35.0 | ml/min | Renal clearance; PO, oral; | DRUGBANK | Clearance | 3.2 | L/h | 37-69 | ml/min | Total clearance; PO, oral; | DRUGBANK |
| Volume of Distribution | 0.10 | L/kg | 0.1 | L/kg | DRUGBANK | |
| Half-life | 3.5 | h | 1.5-5.5 | h | elimination half-life; | DRUGBANK |
| Toxicity Lethal Dose | 1100.0 | mg/kg | 1100.0 | mg/kg | PO, oral; mouse; | DRUGBANK | Toxicity Lethal Dose | 1050.0 | mg/kg | 1050.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity Lethal Dose | 600.0 | mg/kg | 600.0 | mg/kg | subcutaneous injection, SC; mouse; | DRUGBANK | Toxicity Lethal Dose | 630.0 | mg/kg | 630.0 | mg/kg | subcutaneous injection, SC; Rattus, Rat; | DRUGBANK | Toxicity Lethal Dose | 550.0 | mg/kg | 550.0 | mg/kg | Intraperitoneal, IP; mouse; | DRUGBANK | Toxicity Lethal Dose | 530.0 | mg/kg | 530.0 | mg/kg | Intraperitoneal, IP; Rattus, Rat; | DRUGBANK |
| Protein Binding | 94.5 | % | 90-99 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1