Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD13145 ...
Drug Name Nedaplatin
Molecular Weight 303.181
Molecular Formula C2H8N2O3Pt
CAS Number 95734-82-0
SMILES [H][N]([H])([H])[Pt]1(OCC(=O)O1)[N]([H])([H])[H]
External Links
DRUGBANK DB13145
PubChem Compound 9548889

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Water Solubility 10000.0 mg/L 10 mg/ml MSDS

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 4.5 L/h 4.47 L/h DRUGBANK
Clearance 0.24 L/h/kg 4.05 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 12.0 L 12.0 L DRUGBANK
Volume of Distribution 0.67 L/kg 0.67 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 2.1 h 2.1 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Eliminate Route 59.6 % 59.6 % Urinary excretion; DRUGBANK
Protein Binding 50.0 % ~50 % plasma proteins; human, homo sapiens; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1