Basic Information
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| AUC | 2931.0 | ng.h/ml | 2931.0 | ng.h/ml | PO, oral; normal,healthy; | DRUGBANK |
| C Max | 111.0 | ng/ml | 111 | ng/ml | PO, oral; normal,healthy; | DRUGBANK |
| T Max | 7.0 | h | 6-8 | h | PO, oral; chronic liver disease; | DRUGBANK |
| Tss | 120.0 | h | 5 | day | Oral multiple dose; | DRUGBANK |
| Clearance | 18.6 | L/h | 1.1(36.1) | L/h | Average clearance; Hepatitis, Hep; patients; | DRUGBANK |
| Volume of Distribution | 39.5 | L | 39.5(23.5) | L | Apparent volume of distribution; normal,healthy; adults; | DRUGBANK |
| Half-life | 27.0 | h | ~27 | h | elimination half-life; normal,healthy; adults; | DRUGBANK |
| Eliminate Route | 1.0 | % | ~1 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 83.0 | % | ~83 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 13.3 | % | 13.28 | % | Faeces excretion; Unchanged drug; | DRUGBANK |
| Protein Binding | 99.9 | % | >99.9 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1