Basic Information

Drug ID DDPD12839 ...
Drug Name Pegvaliase
Molecular Weight 318.414
Molecular Formula C15H30N2O5
CAS Number 1585984-95-7
SMILES COCCOCCCCCC(=O)NCCCC[C@H](N)C(O)=O
External Links
DRUGBANK DB12839
PubChem Compound 86278362

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
C Max 14000.0 ng/ml 14.0±16.3 mg/L DRUGBANK
C Max 34380.0 ng/ml 0.26-68.5 mg/L DRUGBANK
C Max 16700.0 ng/ml 16.7±19.5 mg/L DRUGBANK
C Max 32020.0 ng/ml 0.24-63.8 mg/L DRUGBANK
T Max 8.0 h 8 h DRUGBANK
T Max 8.0 h 8 h DRUGBANK
Clearance 0.39 L/h 0.39±0.87 L/h apparent clearance; Multiple dose; at steady state; DRUGBANK
Clearance 1.3 L/h 1.25±2.46 L/h apparent clearance; Multiple dose; at steady state; DRUGBANK
Volume of Distribution 121.4 L 1.8-241 L Apparent volume of distribution; at steady state; DRUGBANK
Volume of Distribution 26.3 L 3.1-49.5 L Apparent volume of distribution; subcutaneous injection, SC; DRUGBANK
Half-life 47.0 h 47±42(14-132) h subcutaneous injection, SC; at steady state; DRUGBANK
Half-life 60.0 h 60±45(14-127) h subcutaneous injection, SC; at steady state; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1