Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD12457 ...
Drug Name Rimegepant
Molecular Weight 534.568
Molecular Formula C28H28F2N6O3
CAS Number 1289023-67-1
SMILES N[C@H]1[C@@H](CC[C@@H](OC(=O)N2CCC(CC2)N2C(=O)NC3=NC=CC=C23)C2=C1C=CC=N2)C1=C(F)C(F)=CC=C1
External Links
DRUGBANK DB12457
PubChem Compound 51049968

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Factor Reference
Bioavailability 64.0 % 64 % PO, oral; DRUGBANK
T Max 1.5 h 1.5 h Tablet, PO, oral; DRUGBANK
T Max 2.5 h 2.5 h PO, oral; high-fat meal; high-fat meal ↑ ; DRUGBANK
Volume of Distribution 120.0 L ~120 L at steady state; DRUGBANK
Half-life 11.0 h ~11 h elimination half-life; normal,healthy; DRUGBANK
Eliminate Route 78.0 % 78 % Faeces excretion; PO, oral; normal,healthy; human, homo sapiens; DRUGBANK
Eliminate Route 24.0 % 24 % Urinary excretion; PO, oral; normal,healthy; human, homo sapiens; DRUGBANK
Eliminate Route 32.8 % 32.76 % Faeces excretion; PO, oral; normal,healthy; human, homo sapiens; Unchanged drug; DRUGBANK
Eliminate Route 12.2 % 12.24 % Urinary excretion; PO, oral; normal,healthy; human, homo sapiens; Unchanged drug; DRUGBANK
Protein Binding 96.0 % ~96 % plasma proteins; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1