| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| AUC |
16900.0 |
ng.h/ml |
16900.0 |
ng.h/ml |
|
DRUGBANK |
| C Max |
1940.0 |
ng/ml |
1940 |
ng/ml |
|
DRUGBANK |
| T Max |
1.9 |
h |
1.9 |
h |
|
DRUGBANK |
| Clearance |
47.3 |
L/h |
15.3-79.2 |
L/h |
apparent clearance; Multiple dose; |
DRUGBANK |
Clearance |
16.2 |
L/h |
13.9-18.4 |
L/h |
intravenous injection, IV; Single dose; |
DRUGBANK |
Clearance |
0.26 |
L/h/kg |
4.31 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
187.5 |
L |
113-262 |
L |
Steady state volume of distribution; intravenous injection, IV; Single dose; |
DRUGBANK |
Volume of Distribution |
3.3 |
L/kg |
3.28 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
18.0 |
h |
17-19 |
h |
terminal half-life; Oral single dose; |
DRUGBANK |
Half-life |
16.6 |
h |
16.6 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route |
79.0 |
% |
≥79 |
% |
Faeces excretion; |
DRUGBANK |
| Protein Binding |
70.0 |
% |
70 |
% |
plasma proteins; high protein binding; human, homo sapiens; |
DRUGBANK |
