Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD12278 ...
Drug Name Propiverine
Molecular Weight 367.4813
Molecular Formula C23H29NO3
CAS Number 60569-19-9
SMILES CCCOC(C(=O)OC1CCN(C)CC1)(C1=CC=CC=C1)C1=CC=CC=C1
External Links
DRUGBANK DB12278
PubChem Compound 4942

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Boiling Point 484.2 ℃ 484.2 ℃ MSDS
Melting Point 225.0 ℃ 224-226 ℃ http://www.chemicalbook.com/ChemicalProductProperty_EN_CB3855472.htm
Water Solubility 5000.0 mg/L 5 mg/ml http://www.chemicalbook.com/ChemicalProductProperty_EN_CB3855472.htm

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 40.5 % 40.5 % Tablet, PO, oral; DRUGBANK
T Max 2.3 h 2.3 h PO, oral; DRUGBANK
Clearance 22.3 L/h 371(191–870) ml/min Average clearance; Single dose; DRUGBANK
Clearance 0.18 L/h/kg 2.94 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 2791.0 L 2791(125-4731) L intravenous injection, IV; normal,healthy; DRUGBANK
Volume of Distribution 2.7 L/kg 2.73 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 14.1 h 14.1 h elimination half-life; normal,healthy; different study; DRUGBANK
Half-life 20.1 h 20.1 h elimination half-life; normal,healthy; different study; DRUGBANK
Half-life 22.1 h 22.1 h elimination half-life; normal,healthy; different study; DRUGBANK
Half-life 15.2 h 15.2 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Eliminate Route 60.0 % 60 % Urinary excretion; DRUGBANK
Eliminate Route 21.0 % 21 % Faeces excretion; DRUGBANK
Eliminate Route 1.0 % <1 % Urinary excretion; PO, oral; Unchanged drug; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1