Basic Information
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| AUC | 588000.0 | ng.h/ml | 588.0 | mg.h/l | normal,healthy; adults; | DRUGBANK | AUC | 835000.0 | ng.h/ml | 835.0 | mg.h/l | patients; adults; | DRUGBANK |
| C Max | 55600.0 | ng/ml | 55.6 | mg/L | normal,healthy; adults; | DRUGBANK | C Max | 71300.0 | ng/ml | 71.3 | mg/L | patients; adults; | DRUGBANK |
| Clearance | 8.9 | L/h | 8.9 | L/h | Renal clearance; | DRUGBANK | Clearance | 2.0 | L/h | 2.0 | L/h | Plasma clearance; | DRUGBANK | Clearance | 10.9 | L/h | 10.9 | L/h | intravenous infusion, IV in drop; Multiple dose; normal,healthy; | DRUGBANK | Clearance | 8.0 | L/h | 7.95 | L/h | intravenous infusion, IV in drop; Multiple dose; patients; | DRUGBANK | Clearance | 0.18 | L/h/kg | 2.94 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 18.6 | L | 18.6 | L | Steady state volume of distribution; at steady state; | DRUGBANK | Volume of Distribution | 0.29 | L/kg | 0.29 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 1.7 | h | 1.68 | h | normal,healthy; | DRUGBANK | Half-life | 2.3 | h | 2.25 | h | DRUGBANK | Half-life | 1.3 | h | 1.34 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route | 85.0 | % | ~75-95 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
| Protein Binding | 33.0 | % | ~33 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1