DETAILS

Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID	DDPD12095
Drug Name	Telotristat ethyl
Molecular Weight	574.99
Molecular Formula	C27H26ClF3N6O3
CAS Number	1033805-22-9
SMILES	CCOC(=O)[C@@H](N)CC1=CC=C(C=C1)C1=NC(N)=NC(O[C@H](C2=CC=C(Cl)C=C2N2C=CC(C)=N2)C(F)(F)F)=C1
External Links
	DRUGBANK	DB12095
	PubChem Compound	25025298
	PDR	24051

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Reference
T Max	3.0	h	2-4	h		DRUGBANK
Half-life	8.0	h	4-12	h		DRUGBANK

Maximum Dosage

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Frequency	Brand Name	Component	Reference
Max dose for adults	250.0	mg	250	mg	PO, oral	tid	Xermelo	telotristat ethyl	PDR
Max dose for geriatric	250.0	mg	250	mg	PO, oral	tid	Xermelo	telotristat ethyl	PDR

Drug Property Radar Chart

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1