Basic Information

Drug ID DDPD11994 ...
Drug Name Diacerein
Molecular Weight 368.297
Molecular Formula C19H12O8
CAS Number 13739-02-1
SMILES CC(=O)OC1=CC=CC2=C1C(=O)C1=C(OC(C)=O)C=C(C=C1C2=O)C(O)=O
External Links
DRUGBANK DB11994
PubChem Compound 26248

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 55.0 % 50-60 % DRUGBANK
Clearance 1.5 L/h 1.5 L/h Total clearance; DRUGBANK
Clearance 0.10 L/h 0.1 L/h Renal clearance; DRUGBANK
Volume of Distribution 37.5 L 15-60 L DRUGBANK
Half-life 7.0 h 4-10 h DRUGBANK
Toxicity LD50 6476.0 mg/kg >6476 mg/kg DRUGBANK
Eliminate Route 37.0 % 37 % Urinary excretion; Rattus, Rat; DRUGBANK
Eliminate Route 53.0 % 53 % Urinary excretion; Rattus, Rat; DRUGBANK
Protein Binding 99.0 % 99 % plasma proteins; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1