Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD11989 ...
Drug Name Benznidazole
Molecular Weight 260.253
Molecular Formula C12H12N4O3
CAS Number 22994-85-0
SMILES [O-][N+](=O)C1=NC=CN1CC(=O)NCC1=CC=CC=C1
External Links
DRUGBANK DB11989
PubChem Compound 31593
PDR 24178

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Melting Point 191.0 ℃ 190-192 ℃ MSDS

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 91.7 % 91.7 % DRUGBANK
T Max 2.9 h 2.93 h DRUGBANK
Clearance 2.0 L/h 2.04 L/h apparent clearance; PO, oral; DRUGBANK
Volume of Distribution 39.2 L 39.19 L Apparent volume of distribution; DRUGBANK
Half-life 13.3 h 13.27 h elimination half-life; DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for infants 7.5 mg/kg/day 7.5 mg/kg/day PO, oral Benznidazole benznidazole PDR
Max dose for children 8.0 mg/kgday 8 mg/kgday PO, oral Benznidazole benznidazole PDR
Max dose for children 400.0 mg/day 400 mg/day PO, oral Benznidazole benznidazole PDR
Max dose for children 7.5 mg/kg/day 7.5 mg/kg/day PO, oral Benznidazole benznidazole PDR
Max dose for adolescents 7.0 mg/kg/day 7 mg/kg/day PO, oral Benznidazole benznidazole PDR
Max dose for adults 7.0 mg/kg/day 7 mg/kg/day PO, oral Benznidazole benznidazole PDR
Max dose for geriatric 7.0 mg/kg/day 7 mg/kg/day PO, oral Benznidazole benznidazole PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1