Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD11951 ...
Drug Name Lemborexant
Molecular Weight 410.425
Molecular Formula C22H20F2N4O2
CAS Number 1369764-02-2
SMILES CC1=NC=C(OC[C@]2(C[C@H]2C(=O)NC2=NC=C(F)C=C2)C2=CC=CC(F)=C2)C(C)=N1
External Links
DRUGBANK DB11951
PubChem Compound 56944144

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
T Max 2.0 h 1-3 h DRUGBANK
T Max 4.0 h 3-5 h PO, oral; high-fat meal; DRUGBANK
Metabolic 1.0 % <1 % Urinary excretion; Unchanged drug; DRUGBANK
Volume of Distribution 1970.0 L 1970.0 L DRUGBANK
Half-life 17.0 h 17 h DRUGBANK
Half-life 19.0 h 19 h DRUGBANK
Eliminate Route 57.4 % 57.4 % Faeces excretion; PO, oral; DRUGBANK
Eliminate Route 29.1 % 29.1 % Urinary excretion; PO, oral; DRUGBANK
Eliminate Route 2.9 % <2.91 % Urinary excretion; PO, oral; Unchanged drug; DRUGBANK
Protein Binding 94.0 % ~94 % high protein binding; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1