Basic Information

Drug ID DDPD11859 ...
Drug Name Brexanolone
Molecular Weight 318.4935
Molecular Formula C21H34O2
CAS Number 516-54-1
SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)C(C)=O
External Links
DRUGBANK DB11859
PubChem Compound 92786

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Factor Reference
Bioavailability 5.0 % <5 % PO, oral; adults; DRUGBANK
Clearance 1.0 L/h/kg ~1 l/h/kg Plasma clearance; DRUGBANK
Volume of Distribution 3.0 L/kg ~3 L/kg DRUGBANK
Half-life 9.0 h ~9 h terminal half-life; DRUGBANK
Toxicity MRHD 90.0 ug/kg/h 90.0 ug/kg/h DRUGBANK
Eliminate Route 0.42 % 0.42 % Urinary excretion; Unchanged drug; DRUGBANK
Protein Binding 99.0 % >99 % plasma proteins; Plasma Concentration → ; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1