Basic Information

Drug ID DDPD11791 ...
Drug Name Capmatinib
Molecular Weight 412.428
Molecular Formula C23H17FN6O
CAS Number 1029712-80-8
SMILES CNC(=O)C1=C(F)C=C(C=C1)C1=NN2C(CC3=CC4=C(C=C3)N=CC=C4)=CN=C2N=C1
External Links
DRUGBANK DB11791
PubChem Compound 25145656

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Factor Reference
Bioavailability 70.0 % >70 % PO, oral; DRUGBANK
T Max 1.5 h 1-2 h PO, oral; DRUGBANK
Clearance 24.0 L/h 24.0 L/h apparent clearance; at steady state; DRUGBANK
Volume of Distribution 164.0 L 164.0 L Apparent volume of distribution; at steady state; DRUGBANK
Half-life 6.5 h 6.5 h elimination half-life; DRUGBANK
Eliminate Route 78.0 % ~78 % Faeces excretion; PO, oral; DRUGBANK
Eliminate Route 22.0 % ~22 % Urinary excretion; PO, oral; DRUGBANK
Eliminate Route 32.8 % ~32.76 % Faeces excretion; PO, oral; Unchanged drug; DRUGBANK
Protein Binding 96.0 % ~96 % plasma proteins; Plasma Concentration → ; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1