Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD11732 ...
Drug Name Lasmiditan
Molecular Weight 377.367
Molecular Formula C19H18F3N3O2
CAS Number 439239-90-4
SMILES CN1CCC(CC1)C(=O)C1=CC=CC(NC(=O)C2=C(F)C=C(F)C=C2F)=N1
External Links
DRUGBANK DB11732
PubChem Compound 11610526

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
AUC 1892.0 ng.h/ml 1892±746.0 ng.h/ml PO, oral; DRUGBANK
AUC 2251.5 ng.h/ml 2251.48 ng.h/ml PO, oral; high-fat meal; DRUGBANK
Bioavailability 40.0 % 40 % PO, oral; DRUGBANK
C Max 322.8 ng/ml 322.8±122.0 ng/ml PO, oral; DRUGBANK
C Max 393.8 ng/ml 393.82 ng/ml PO, oral; high-fat meal; DRUGBANK
T Max 1.8 h 1.8 h PO, oral; DRUGBANK
T Max 2.8 h 2.8 h PO, oral; high-fat meal; DRUGBANK
Half-life 5.7 h 5.7 h elimination half-life; DRUGBANK
Eliminate Route 3.0 % 3 % Urinary excretion; Unchanged drug; DRUGBANK
Protein Binding 57.5 % ~55-60 % plasma proteins; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1