Basic Information

Drug ID DDPD11730 ...
Drug Name Ribociclib
Molecular Weight 434.548
Molecular Formula C23H30N8O
CAS Number 1211441-98-3
SMILES CN(C)C(=O)C1=CC2=CN=C(NC3=CC=C(C=N3)N3CCNCC3)N=C2N1C1CCCC1
External Links
DRUGBANK DB11730
PubChem Compound 44631912
PDR 24052

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
T Max 3.0 h 1-5 h DRUGBANK
Tss 192.0 h 8 day DRUGBANK
Half-life 32.6 h 32.6 h DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Frequency Brand Name Component Reference
Max dose for adults 600.0 mg/day 600 mg/day PO, oral qd Kisqali ribociclib PDR
Max dose for geriatric 600.0 mg/day 600 mg/day PO, oral qd Kisqali ribociclib PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1