Basic Information
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 95.0 | % | >95 | % | PO, oral; | DRUGBANK |
| Bioavailability | 60.0 | % | 60 | % | PO, oral; | DRUGBANK |
| T Max | 3.0 | h | 3 | h | PO, oral; | DRUGBANK |
| Metabolic | 83.3 | % | 83.33 | % | Urinary excretion; | DRUGBANK | Metabolic | 16.7 | % | 16.67 | % | Faeces excretion; | DRUGBANK |
| Clearance | 108.0 | L/h | 1800.0 | ml/min | DRUGBANK | Clearance | 1.6 | L/h/kg | 26 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 500.0 | L | 400-600 | L | DRUGBANK | Volume of Distribution | 9.7 | L/kg | 9.7 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 5.7 | h | 5.7 | h | DRUGBANK | Half-life | 5.6 | h | 5.6 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 | 265.0 | mg/kg | 265.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK |
| Eliminate Route | 15.0 | % | 15 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 8.0 | % | ~8 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
| Protein Binding | 71.0 | % | 71 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1