Basic Information
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 62.0 | % | 62 | % | PO, oral; adults; | DRUGBANK |
| T Max | 1.3 | h | 1-1.5 | h | DRUGBANK | |
| Clearance | 8.8 | L/h | 8.8 | L/h | pediatric patients; | DRUGBANK | Clearance | 15.7 | L/h | 15.7 | L/h | normal,healthy; adults; Male, men; | DRUGBANK | Clearance | 12.6 | L/h | 9.2-15.9 | L/h | Asian; | DRUGBANK |
| Volume of Distribution | 124.5 | L | 78-171 | L | Apparent volume of distribution; at steady state; pediatric patients; | DRUGBANK | Volume of Distribution | 146.0 | L | 146.0 | L | Apparent volume of distribution; normal,healthy; Male, men; adults; | DRUGBANK | Volume of Distribution | 110.7 | L | 73.2-148.1 | L | Apparent volume of distribution; at steady state; dose; patients; Asian; | DRUGBANK |
| Half-life | 6.2 | h | 6.2 | h | elimination half-life; Children; patients; | DRUGBANK | Half-life | 9.9 | h | 9.2-10.6 | h | Asian; patients; | DRUGBANK | Half-life | 13.0 | h | ~13 | h | different study; | DRUGBANK |
| Eliminate Route | 59.0 | % | ~59 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 33.0 | % | ~33 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 96.0 | % | 96 | % | DRUGBANK | Protein Binding | 35.0 | % | <35 | % | DRUGBANK | Protein Binding | 98.4 | % | ~98.4 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1